kjøpe viagra i norge Things To Know Before You Buy
kjøpe viagra i norge Things To Know Before You Buy
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Seksuell aktivitet kan være ekstra belastende for hjertet. Dersom du har hjerteproblemer eller tror du kan ha et hjerteproblem er det viktig at du opplyser om dette i samtalen med farmasøyten i apotek.
It is eradicated predominantly by hepatic metabolism (primarily CYP3A4) and is also transformed to an Energetic metabolite with properties similar to the mum or dad, sildenafil. Both equally sildenafil as well as the metabolite have terminal fifty percent life of about 4 several hours.
Nevertheless, there are no managed clinical info on the protection or efficacy of VIAGRA in sufferers with sickle mobile or associated anemias.
Use with caution in individuals with the following underlying disorders that may be specially sensitive towards the steps of vasodilators which include VIAGRA – People with left ventricular outflow obstruction (e.
Snakk med lege før du tar legemidlet dersom du har høyt blodtrykk som ikke er godt behandlet eller uregelmessige hjerteslag/hjertebank. Les pakningen og pakningsvedlegget nøye før bruk. Her kan du finne mer informasjon om Viagra Reseptfri og impotens.
Nosebleeds. Sildenafil may possibly trigger nosebleeds. You may well be at higher hazard for this if you are taking a blood thinner medicine. Convey to your healthcare service provider if you can get nosebleeds generally even though having sildenafil. If the nosebleed is serious or will not end after making use of force, get assistance immediately.
Solitary oral doses of sildenafil approximately one hundred mg developed no clinically appropriate modifications from the ECGs of regular male volunteers.
Sildenafil enhances the impact of NO click here by inhibiting phosphodiesterase variety 5 (PDE5), and that is chargeable for degradation of cGMP inside the corpus cavernosum. Sildenafil has no direct relaxant impact on isolated human corpus cavernosum.
Medical professionals must advise individuals to prevent usage of all PDE5 inhibitors, like VIAGRA, and find health-related notice while in the occasion of a unexpected loss of vision in one or equally eyes. This kind of an occasion may be a indicator of non-arteritic anterior ischemic optic neuropathy (NAION), a reason behind reduced vision which include doable long term loss of eyesight, which has been noted hardly ever publish-advertising and marketing in temporal association with the use of all PDE5 inhibitors. It really is impossible to find out whether these occasions are associated straight to the use of PDE5 inhibitors or to other things.
Men and women with “crowded” optic disc can also be viewed as at better hazard for NAION in comparison to the overall inhabitants, nevertheless, evidence is insufficient to assist screening of possible buyers of PDE5 inhibitors, such as VIAGRA, for this uncommon situation.
Sildenafil was destructive in in vitro bacterial and Chinese hamster ovary cell assays to detect mutagenicity, As well as in vitro human lymphocytes As well as in vivo mouse micronucleus assays to detect clastogenicity.
Also, N-desmethyl metabolite AUC and Cmax values drastically elevated by two hundred% and 79%, respectively in topics with critical renal impairment when compared to subjects with normal renal function.
The next adverse reactions are actually recognized all through publish approval utilization of VIAGRA. Because these reactions are noted voluntarily from a populace of uncertain measurement, It is far from always feasible to reliably estimate their frequency or establish a causal partnership to drug exposure.
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